Ethyl 2-(2-aminothiazol-5-ylthio)acetate → HCID 57776319, compound

HRID 1361544Notes

Reaction equation

HRID 1361544 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:21]=[C:22]([F:24])[CH:23]=1)[O:5][C:6]1[CH:7]=[C:8]([CH:12]=[C:13]([O:15][C@@H:16]([CH3:20])[CH2:17][O:18][CH3:19])[CH:14]=1)[C:9]([OH:11])=O.[CH2:25]([O:27][C:28](=[O:37])[CH2:29][S:30][C:31]1[S:35][C:34]([NH2:36])=[N:33][CH:32]=1)[CH3:26]>>[CH2:25]([O:27][C:28](=[O:37])[CH2:29][S:30][C:31]1[S:35][C:34]([NH:36][C:9](=[O:11])[C:8]2[CH:12]=[C:13]([O:15][C@@H:16]([CH3:20])[CH2:17][O:18][CH3:19])[CH:14]=[C:6]([O:5][C:4]3[CH:21]=[C:22]([F:24])[CH:23]=[C:2]([F:1])[CH:3]=3)[CH:7]=2)=[N:33][CH:32]=1)[CH3:26]

Participants

3

Reactant 2

HCID 21455623Ethyl 2-(2-aminothiazol-5-ylthio)acetateHCID 59842405HCID 59842405, compound

Product 1

HCID 57776319HCID 57776319, compound

Procedure

The title compound was prepared from 3-(3,5-difluoro-phenoxy)-5-((S)-2-methoxy-1-methyl-ethoxy)-benzoic acid and (2-amino-thiazol-5-ylsulfanyl)-acetic acid ethyl ester following general procedure A

Sources & evidence

ORD record
ord-3aa0fa4eaa2244289579f0f1bdc08cd1
Source dataset
uspto-grants-2011_02
Patent number
US07880012B2

Reaction notes

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