Ethyl 2-(2-aminothiazol-5-ylthio)acetate → HCID 57776285, compound

HRID 1361548Notes

Reaction equation

HRID 1361548 reaction equation
[F:1][CH2:2][CH:3]([CH2:22][F:23])[O:4][C:5]1[CH:6]=[C:7]([CH:11]=[C:12]([O:14][C:15]2[CH:20]=[CH:19][C:18]([F:21])=[CH:17][CH:16]=2)[CH:13]=1)[C:8]([OH:10])=O.[CH2:24]([O:26][C:27](=[O:36])[CH2:28][S:29][C:30]1[S:34][C:33]([NH2:35])=[N:32][CH:31]=1)[CH3:25]>>[CH2:24]([O:26][C:27](=[O:36])[CH2:28][S:29][C:30]1[S:34][C:33]([NH:35][C:8](=[O:10])[C:7]2[CH:11]=[C:12]([O:14][C:15]3[CH:20]=[CH:19][C:18]([F:21])=[CH:17][CH:16]=3)[CH:13]=[C:5]([O:4][CH:3]([CH2:2][F:1])[CH2:22][F:23])[CH:6]=2)=[N:32][CH:31]=1)[CH3:25]

Participants

3

Reactant 2

HCID 21455623Ethyl 2-(2-aminothiazol-5-ylthio)acetateHCID 66970020HCID 66970020, compound

Product 1

HCID 57776285HCID 57776285, compound

Procedure

The title compound was prepared from 3-(2-fluoro-1-fluoromethyl-ethoxy)-5-(4-fluoro-phenoxy)-benzoic acid and (2-amino-thiazol-5-ylsulfanyl)-acetic acid ethyl ester following general procedure A

Sources & evidence

ORD record
ord-f046ae5fe60843fba59aab703acea04a
Source dataset
uspto-grants-2011_02
Patent number
US07880012B2

Reaction notes

Loading…