Ethyl 2-(2-aminothiazol-5-ylthio)acetate → HCID 57776301, compound

HRID 1361549Notes

Reaction equation

HRID 1361549 reaction equation
[C@H:1]([O:5][C:6]1[CH:7]=[C:8]([CH:12]=[C:13]([O:15][C:16]2[CH:21]=[CH:20][C:19]([F:22])=[CH:18][CH:17]=2)[CH:14]=1)[C:9]([OH:11])=O)([CH2:3][CH3:4])[CH3:2].[CH2:23]([O:25][C:26](=[O:35])[CH2:27][S:28][C:29]1[S:33][C:32]([NH2:34])=[N:31][CH:30]=1)[CH3:24]>>[CH2:23]([O:25][C:26](=[O:35])[CH2:27][S:28][C:29]1[S:33][C:32]([NH:34][C:9](=[O:11])[C:8]2[CH:12]=[C:13]([O:15][C:16]3[CH:21]=[CH:20][C:19]([F:22])=[CH:18][CH:17]=3)[CH:14]=[C:6]([O:5][C@@H:1]([CH2:3][CH3:4])[CH3:2])[CH:7]=2)=[N:31][CH:30]=1)[CH3:24]

Participants

3

Reactant 2

HCID 21455623Ethyl 2-(2-aminothiazol-5-ylthio)acetateHCID 66969772HCID 66969772, compound

Product 1

HCID 57776301HCID 57776301, compound

Procedure

The title compound was prepared from 3-((R)-sec-butoxy)-5-(4-fluoro-phenoxy)benzoic acid and (2-amino-thiazol-5-ylsulfanyl)-acetic acid ethyl ester following general procedure A

Sources & evidence

ORD record
ord-e3886838d21d413088b0c56a180d4b34
Source dataset
uspto-grants-2011_02
Patent number
US07880012B2

Reaction notes

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