Ethyl 2-(2-aminothiazol-5-ylthio)acetate → HCID 57776329, compound

HRID 1361552Notes

Reaction equation

HRID 1361552 reaction equation
[CH3:1][O:2][CH2:3][C@H:4]([CH3:22])[O:5][C:6]1[CH:7]=[C:8]([CH:12]=[C:13]([O:15][CH2:16][C:17]2[CH:21]=[CH:20][S:19][CH:18]=2)[CH:14]=1)[C:9]([OH:11])=O.[CH2:23]([O:25][C:26](=[O:35])[CH2:27][S:28][C:29]1[S:33][C:32]([NH2:34])=[N:31][CH:30]=1)[CH3:24]>>[CH2:23]([O:25][C:26](=[O:35])[CH2:27][S:28][C:29]1[S:33][C:32]([NH:34][C:9](=[O:11])[C:8]2[CH:12]=[C:13]([O:15][CH2:16][C:17]3[CH:21]=[CH:20][S:19][CH:18]=3)[CH:14]=[C:6]([O:5][C@@H:4]([CH3:22])[CH2:3][O:2][CH3:1])[CH:7]=2)=[N:31][CH:30]=1)[CH3:24]

Participants

3

Reactant 2

HCID 21455623Ethyl 2-(2-aminothiazol-5-ylthio)acetateHCID 66969861HCID 66969861, compound

Product 1

HCID 57776329HCID 57776329, compound

Procedure

The title compound was prepared from 3-((S)-2-methoxy-1-methyl-ethoxy)-5-(thiophen-3-ylmethoxy)-benzoic acid and (2-amino-thiazol-5-ylsulfanyl)-acetic acid ethyl ester following general procedure A

Sources & evidence

ORD record
ord-044a909ffccb40cd911e4383b2f17d53
Source dataset
uspto-grants-2011_02
Patent number
US07880012B2

Reaction notes

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