3,5-Diisopropoxybenzoic acid-1G → 3-[2-(3,5-Diisopropoxy-benzoylamino)-thiazol-4-ylmethylsulfanyl]-propionic acid ethyl ester

HRID 1361553Notes

Reaction equation

HRID 1361553 reaction equation
[CH:1]([O:4][C:5]1[CH:6]=[C:7]([CH:11]=[C:12]([O:14][CH:15]([CH3:17])[CH3:16])[CH:13]=1)[C:8]([OH:10])=O)([CH3:3])[CH3:2].[CH2:18]([O:20][C:21](=[O:32])[CH2:22][CH2:23][S:24][CH2:25][C:26]1[N:27]=[C:28]([NH2:31])[S:29][CH:30]=1)[CH3:19]>>[CH2:18]([O:20][C:21](=[O:32])[CH2:22][CH2:23][S:24][CH2:25][C:26]1[N:27]=[C:28]([NH:31][C:8](=[O:10])[C:7]2[CH:11]=[C:12]([O:14][CH:15]([CH3:17])[CH3:16])[CH:13]=[C:5]([O:4][CH:1]([CH3:2])[CH3:3])[CH:6]=2)[S:29][CH:30]=1)[CH3:19]

Participants

3

Reactant 2

HCID 205341403,5-Diisopropoxybenzoic acid-1GHCID 71414389Ethyl 3-{[(2-amino-1,3-thiazol-4-YL)methyl]sulfanyl}propanoate

Product 1

HCID 866323863-[2-(3,5-Diisopropoxy-benzoylamino)-thiazol-4-ylmethylsulfanyl]-propionic acid ethyl ester

Procedure

3-[2-(3,5-Diisopropoxy-benzoylamino)-thiazol-4-ylmethylsulfanyl]-propionic acid ethyl ester was prepared from 3,5-diisopropoxy-benzoic acid and 3-(2-amino-thiazol-4-ylmethylsulfanyl)-propionic acid ethyl ester following general procedure A.

Sources & evidence

ORD record
ord-3c9f01ccabfc4155be956464f9ec8f45
Source dataset
uspto-grants-2011_02
Patent number
US07880012B2

Reaction notes

Loading…