3-Isopropyloxy-5-phenoxybenzoic acid → 3-[2-(3-Isopropoxy-5-phenoxy-benzoylamino)-thiazol-4-ylmethylsulfanyl]-propionic acid ethyl ester

HRID 1361554Notes

Reaction equation

HRID 1361554 reaction equation
[CH:1]([O:4][C:5]1[CH:6]=[C:7]([CH:11]=[C:12]([O:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:13]=1)[C:8]([OH:10])=O)([CH3:3])[CH3:2].[CH2:21]([O:23][C:24](=[O:35])[CH2:25][CH2:26][S:27][CH2:28][C:29]1[N:30]=[C:31]([NH2:34])[S:32][CH:33]=1)[CH3:22]>>[CH2:21]([O:23][C:24](=[O:35])[CH2:25][CH2:26][S:27][CH2:28][C:29]1[N:30]=[C:31]([NH:34][C:8](=[O:10])[C:7]2[CH:11]=[C:12]([O:14][C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[CH:13]=[C:5]([O:4][CH:1]([CH3:2])[CH3:3])[CH:6]=2)[S:32][CH:33]=1)[CH3:22]

Participants

3

Reactant 2

HCID 669698623-Isopropyloxy-5-phenoxybenzoic acidHCID 71414389Ethyl 3-{[(2-amino-1,3-thiazol-4-YL)methyl]sulfanyl}propanoate

Product 1

HCID 866323873-[2-(3-Isopropoxy-5-phenoxy-benzoylamino)-thiazol-4-ylmethylsulfanyl]-propionic acid ethyl ester

Procedure

3-[2-(3-Isopropoxy-5-phenoxy-benzoylamino)-thiazol-4-ylmethylsulfanyl]-propionic acid ethyl ester was prepared from 3-isopropoxy-5-phenoxy-benzoic acid and 3-(2-amino-thiazol-4-ylmethylsulfanyl)-propionic acid ethyl ester following general procedure A.

Sources & evidence

ORD record
ord-30f59f9602b549cbabd24b96bb7a42a7
Source dataset
uspto-grants-2011_02
Patent number
US07880012B2

Reaction notes

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