HuagongsheHuagongshe Chemistry Print Report · For research reference only
N~1~-[3-(dimethylamino)propyl]-N~1~-methyl-4-(trifluoromethyl)benzene-1,2-diamine → N-(2-((3-(dimethylamino)propyl)(methyl)amino)-5-(trifluoromethyl)phenyl)-N'-(3-methyl-4-((3-(4-pyrimidinyl)-2-pyridinyl)oxy)phenyl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N~1~-[3-(dimethylamino)propyl]-N~1~-methyl-4-(trifluoromethyl)benzene-1,2-diamine | HCID 16109009 | — |
| Reactant | 4-(2-(4-Isocyanato-2-methylphenoxy)pyridin-3-yl)pyrimidine | HCID 86602595 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | N-(2-((3-(dimethylamino)propyl)(methyl)amino)-5-(trifluoromethyl)phenyl)-N'-(3-methyl-4-((3-(4-pyrimidinyl)-2-pyridinyl)oxy)phenyl)urea | HCID 58396469 | — |
Reaction Steps
To 4-(2-(4-isocyanato-2-methylphenoxy)pyridin-3-yl)pyrimidine (93 mg, 0.33 mmol) in toluene (3 mL) was added N1-(3-(dimethylamino)propyl)-N1-methyl-4-(trifluoromethyl)benzene-1,2-diamine (82 mg, 0.30 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07880000B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-ac2a56a31fb34ebcbfce3a285d35081c |
| Source note | uspto-grants-2011_02 |