HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl acrylate → 2,3-dihydro-8-(methylaminomethyl)-1H-3a-azacyclopenta[a]indene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl acrylate | HCID 15458 | — |
| Reactant | 1,3-dimethyl-1H-indole-2-carbaldehyde | HCID 2771468 | — |
| Reactant | 2,3-dihydro-1H-3a-azacyclopenta[a]indene-8-carboxaldehyde | HCID 5323989 | — |
| Product | 2,3-dihydro-8-(methylaminomethyl)-1H-3a-azacyclopenta[a]indene | HCID 22139048 | 54% |
Reaction Steps
According to the procedure of Preparation 13 (c), except substituting 2,3-dihydro-1H-3a-azacyclopenta[α]indene-8-carboxaldehyde (0.17 g, 0.92 mmole) for the 1,3-dimethyl-1H-indole-2-carboxaldehyde, the title compound (0.1 g, 54%) was prepared as a yellow oil: MS (ES) m/e 201 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07879872B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-c66a235b131248f88429ef88d7532017 |
| Source note | uspto-grants-2011_02 |