HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-dimethyl-1H-indole-2-carbaldehyde → 7-Chloro-N,1-dimethyl-1H-indole-3-methanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-dimethyl-1H-indole-2-carbaldehyde | HCID 2771468 | — |
| Reactant | Methyl 2-((5-bromopyridin-2-yl)amino)acetate | HCID 22139049 | — |
| Reactant | 7-chloro-1-methyl-1H-indole-3-carbaldehyde | HCID 22139146 | — |
| Product | 7-Chloro-N,1-dimethyl-1H-indole-3-methanamine | HCID 22139067 | 93% |
Reaction Steps
According to the procedure of Preparation 13 (c), except substituting 7-chloro-1-methyl-1H-indole-3-carboxaldehyde for the 1,3-dimethyl-1H-indole-2-carboxaldehyde, the title compound (2.0 g, 93%) was obtained as an amber oil: MS (ES) m/e 209.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07879872B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-1a58c313c9e248d391ea6b78a78bf570 |
| Source note | uspto-grants-2011_02 |