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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1362001Generated: October 28, 2026

Skatole → 5-Chloro-1-methylindole

https://huagongshe.com/reaction/1362001

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSkatoleHCID 6736—
Reactant5-ChloroindoleHCID 87110—
Product5-Chloro-1-methylindoleHCID 1085584391%

Reaction Steps

According to the procedure of Preparation 13 (a), except substituting 5-chloroindole for the 3-methylindole, the title compound (2.0 g, 91%) was obtained as an amber oil: MS (ES) m/e 166.0 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07879872B2
Source datasetuspto-grants-2011_02
ORD IDord-4f0abf1742734a9bb2c2190a87eef802
Source noteuspto-grants-2011_02