HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-chloro-1H-indole-3-carbaldehyde → 7-chloro-3-(methylaminomethyl)-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-chloro-1H-indole-3-carbaldehyde | HCID 643958 | — |
| Reactant | 1,3-dimethyl-1H-indole-2-carbaldehyde | HCID 2771468 | — |
| Reactant | Methyl 2-((5-bromopyridin-2-yl)amino)acetate | HCID 22139049 | — |
| Product | 7-chloro-3-(methylaminomethyl)-1H-indole | HCID 22139004 | 92% |
Reaction Steps
According to the procedure of Preparation 13 (c), except substituting 7-chloro-1H-indole-3-carboxaldehyde for the 1,3-dimethyl-1H-indole-2-carboxaldehyde, the title compound (440 mg, 92%) was obtained as an off white solid: MS (ES) m/e 195.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07879872B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-31ffc9774c194c049e4dafd7d93f0e0d |
| Source note | uspto-grants-2011_02 |