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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1362023Generated: October 25, 2026

3-Formyl-2-methylindole → 6-methoxy-1-methyl-3-(methylaminomethyl)-1H-indole

https://huagongshe.com/reaction/1362023

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Formyl-2-methylindoleHCID 73166—
Reactant6-Methoxy-1-methyl-1H-indole-3-carbaldehydeHCID 1382010—
Product6-methoxy-1-methyl-3-(methylaminomethyl)-1H-indoleHCID 2213911787%

Reaction Steps

According to the procedure of Preparation 12, except substituting 6-methoxy-1-methyl-1H-indole-3-carboxaldehyde for the 2-methylindole-3-carboxaldehyde, the title compound (2.1 g, 87%) was obtained as an oil: MS (ES) m/e 205.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07879872B2
Source datasetuspto-grants-2011_02
ORD IDord-e78cc2e2f08b49469ec8f49d1b1f960b
Source noteuspto-grants-2011_02