2-Naphthoyl chloride → 3-{4-[(Naphthalene-2-carbonyl)-amino]-phenyl)-acrylic acid methyl ester

Participants

Reaction Steps

Using an analogous method (H4), the title compound was prepared from 2-naphthalenecarbonyl chloride (0.557 g, 2.91 mmol) and 3-(4-amino-phenyl)-acrylic acid methyl ester (3) in a form of white solid (0.950 g, 75%). 1H NMR (DMSO-d6, HMDSO), δ: 3.65 (3H, s); 6.51 (1H, d, J=16.0 Hz); 7.47-8.25 (12H, m); 10.63 (1H, s).

Provenance & Evidence