Phosphorus oxychloride → 3-Chloro-5-phenyl-pyridazine-4-carbonitrile

Participants

Reaction Conditions

Reaction Steps

3-Oxo-5-phenyl-2,3-dihydro-pyridazine-4-carbonitrile (70 mg) was suspended in 1 mL phosphorous oxychloride and heated to 100° C. for 6 hours. The mixture was then cooled and poured onto ice. The resulting brown solid product was filtered and air dried and used in the next step without further purification.

Provenance & Evidence