HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 46833681, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | m-Anisoyl chloride | HCID 74374 | — |
| Reactant | 4-(2-bromo-ethoxy)-3-(2-methyl-2H-pyrazol-3-yl)-phenylamine | HCID 46833680 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 46833681 | HCID 46833681 | 65.1% |
Reaction Steps
A mixture of 4-(2-Bromoethoxy)-3-(2-methyl-2H-pyrazol-3-yl)-phenylamine (1.012 g, 3.417 mmole), 3-methoxy-benzoyl chloride (700 mg, 1.2 eq), and triethylamine (1.0 mL, 2 eq) in 5 mL THF was stirred at room temperature for 10 minutes. The mixture was purified by HPLC to give title compound as white solid (957 mg, 52%). Exact mass calculated for C20H20BrN3O3429.1. found 430.3 (M+H 79Br, 100), 432.5 (M+H 18Br, 98).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07884101B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-c94738aa762346488466490ea08deb89 |
| Source note | uspto-grants-2011_02 |