p-Toluenesulfonic acid → HCID 24738172, compound

Participants

Reaction Steps

100 mg of 5-(3-amino-1H-indazol-5-yl)furan-2-carboxylic acid and 78 mg of p-toluenesulfonic acid are heated at 75° C. for 3 days in 5 ml of ethanol. The batch is evaporated, water is added, and the mixture is neutralised. The mixture is extracted three times with EA, the combined org. phases are washed with water, dried and evaporated to dryness. Purification by RP chromatography gives 30 mg of ethyl 5-(3-amino-1H-indazol-5-yl)furan-2-carboxylate, corresponding to a yield of 27%.

Provenance & Evidence