tert-Butyl 6-chloro-1,2,3,4-tetrahydroquinolin-3-ylcarbamate → N-(6-chloro-1,2,3,4-tetrahydroquinolin-3-yl)benzenesulfonamide

HRID 1363086Notes

Reaction equation

HRID 1363086 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[NH:8][CH2:7][CH:6]([NH:12]C(=O)OC(C)(C)C)[CH2:5]2.C(C1C=C2C(=CC=1)NC[C@@H](N[S:33]([C:36]1[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=1)(=[O:35])=[O:34])C2)#N>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[NH:8][CH2:7][CH:6]([NH:12][S:33]([C:36]1[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=1)(=[O:35])=[O:34])[CH2:5]2

Participants

3

Reactant 2

HCID 59297067tert-Butyl 6-chloro-1,2,3,4-tetrahydroquinolin-3-ylcarbamateHCID 66757946(S)-N-(6-Cyano-1,2,3,4-tetrahydro-quinolin-3-yl)-benzenesulfonamide

Product 1

HCID 59778174N-(6-chloro-1,2,3,4-tetrahydroquinolin-3-yl)benzenesulfonamide

Procedure

Compound 21B was prepared from 21A by procedures analogous to those described in Example 1D and 1G.

Sources & evidence

ORD record
ord-371caebccc874a979f3ef72afc419e94
Source dataset
uspto-grants-2011_02
Patent number
US07884113B2

Reaction notes

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