HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-chloro-4H-thieno[3,2-b]pyrrole-5-carboxylate → HCID 59648579, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-chloro-4H-thieno[3,2-b]pyrrole-5-carboxylate | HCID 57348924 | — |
| Reactant | Ethyl 3-bromo-4H-furo[3,2-b]pyrrole-5-carboxylate | HCID 59648581 | — |
| Solvent | Ethylacetate heptane | HCID 21899848 | — |
| Product | HCID 59648579 | HCID 59648579 | 42% |
Reaction Steps
The title compound was synthesized from ethyl 3-bromo-4H-furo[3,2-b]pyrrole-5-carboxylate (200 mg, 0.774 mmol) using the conditions to synthesize ethyl 3-chloro-4H-thieno[3,2-b]pyrrole-5-carboxylate. Chromatography (silica gel, heptane/EtOAc) yielded ethyl 3-chloro-4H-furo[3,2-b]pyrrole-5-carboxylate (70 mg, 42% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07884124B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-4b159802e4c2467d91b226eb472f5f8f |
| Source note | uspto-grants-2011_02 |