Pyridinium chloride → HCID 66933725, compound

HRID 1363343Notes

Reaction equation

HRID 1363343 reaction equation
[Br:1][C:2]1[CH:7]=[C:6]([N+:8]([O-:10])=[O:9])[CH:5]=[CH:4][C:3]=1[C:11]1[O:12][C:13]2[C:18]([C:19](=[O:21])[CH:20]=1)=[C:17]([O:22]C)[CH:16]=[C:15]([O:24]C)[C:14]=2[C@@H:26]1[CH2:30][CH2:29][N:28]([CH3:31])[C@H:27]1[CH2:32][OH:33].Cl.N1C=CC=CC=1>>[Br:1][C:2]1[CH:7]=[C:6]([N+:8]([O-:10])=[O:9])[CH:5]=[CH:4][C:3]=1[C:11]1[O:12][C:13]2[C:18]([C:19](=[O:21])[CH:20]=1)=[C:17]([OH:22])[CH:16]=[C:15]([OH:24])[C:14]=2[C@@H:26]1[CH2:30][CH2:29][N:28]([CH3:31])[C@H:27]1[CH2:32][OH:33]

Participants

3

Reactant 2

HCID 10176127Pyridinium chlorideHCID 66933788HCID 66933788, compound

Product 1

HCID 66933725HCID 66933725, compound

Procedure

Compound of example 41 (0.3 g, 0.6 mmol) was demethylated using pyridine hydrochloride (3 g, 26 mmol) as described in example 17 to obtain the title compound.

Sources & evidence

ORD record
ord-d07316b9e3e648ee9a4f2d185603830c
Source dataset
uspto-grants-2011_02
Patent number
US07884127B2

Reaction notes

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