Pyridinium chloride → HCID 66933734, compound

HRID 1363353Notes

Reaction equation

HRID 1363353 reaction equation
[OH:1][CH2:2][C@H:3]1[C@H:7]([C:8]2[C:9]([O:30]C)=[CH:10][C:11]([O:28]C)=[C:12]3[C:17]=2[O:16][C:15]([C:18]2[CH:25]=[CH:24][C:21]([C:22]#[N:23])=[CH:20][C:19]=2[CH3:26])=[CH:14][C:13]3=[O:27])[CH2:6][CH2:5][N:4]1[CH3:32].Cl.N1C=CC=CC=1>>[OH:28][C:11]1[CH:10]=[C:9]([OH:30])[C:8]([C@@H:7]2[CH2:6][CH2:5][N:4]([CH3:32])[C@H:3]2[CH2:2][OH:1])=[C:17]2[C:12]=1[C:13](=[O:27])[CH:14]=[C:15]([C:18]1[CH:25]=[CH:24][C:21]([C:22]#[N:23])=[CH:20][C:19]=1[CH3:26])[O:16]2

Participants

3

Reactant 2

HCID 10176127Pyridinium chlorideHCID 66934060HCID 66934060, compound

Product 1

HCID 66933734HCID 66933734, compound

Procedure

Compound of example 59 (0.6 g, 1.38 mmol) was demethylated using pyridine hydrochloride (6 g, 51.95 mmol) as described in example 17 to obtain the title compound.

Sources & evidence

ORD record
ord-89da4e832f6041708240730cd6aea9c7
Source dataset
uspto-grants-2011_02
Patent number
US07884127B2

Reaction notes

Loading…