Pyridinium chloride → HCID 66933663, compound

HRID 1363356Notes

Reaction equation

HRID 1363356 reaction equation
[OH:1][CH2:2][C@H:3]1[C@H:7]([C:8]2[C:9]([O:26]C)=[CH:10][C:11]([O:24]C)=[C:12]3[C:17]=2[O:16][C:15]([C:18]2[S:19][CH:20]=[CH:21][CH:22]=2)=[CH:14][C:13]3=[O:23])[CH2:6][CH2:5][N:4]1[CH3:28].Cl.N1C=CC=CC=1>>[OH:24][C:11]1[CH:10]=[C:9]([OH:26])[C:8]([C@@H:7]2[CH2:6][CH2:5][N:4]([CH3:28])[C@H:3]2[CH2:2][OH:1])=[C:17]2[C:12]=1[C:13](=[O:23])[CH:14]=[C:15]([C:18]1[S:19][CH:20]=[CH:21][CH:22]=1)[O:16]2

Participants

3

Reactant 2

HCID 10176127Pyridinium chlorideHCID 66933780HCID 66933780, compound

Product 1

HCID 66933663HCID 66933663, compound

Procedure

Compound of example 67 (0.29 g, 0.72 mmol) of was subjected to demethylation using pyridine hydrochloride (2.9 g, 25.11 mmol) as described in example 17 to obtain the title compound.

Sources & evidence

ORD record
ord-eaf3881adb5d478387c2ea64f732f3d0
Source dataset
uspto-grants-2011_02
Patent number
US07884127B2

Reaction notes

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