Pyridinium chloride → HCID 66933697, compound

HRID 1363358Notes

Reaction equation

HRID 1363358 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[O:9][C:10]3[C:15]([C:16](=[O:18])[CH:17]=2)=[C:14]([O:19]C)[CH:13]=[C:12]([O:21]C)[C:11]=3[C@@H:23]2[CH2:27][CH2:26][N:25]([CH3:28])[C@H:24]2[CH2:29][OH:30])[CH:5]=[CH:6][CH:7]=1.Cl.N1C=CC=CC=1>>[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[O:9][C:10]3[C:15]([C:16](=[O:18])[CH:17]=2)=[C:14]([OH:19])[CH:13]=[C:12]([OH:21])[C:11]=3[C@@H:23]2[CH2:27][CH2:26][N:25]([CH3:28])[C@H:24]2[CH2:29][OH:30])[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 10176127Pyridinium chlorideHCID 66933637HCID 66933637, compound

Product 1

HCID 66933697HCID 66933697, compound

Procedure

Compound of example 73 (0.25 g, 0.58 mmol) was subjected to demethylation using pyridine hydrochloride (2.5 g, 21.64 mmol) as described in example 17 to afford the title compounds.

Sources & evidence

ORD record
ord-7ffda5bb880649bca9a018ebb8c8fd93
Source dataset
uspto-grants-2011_02
Patent number
US07884127B2

Reaction notes

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