Pyridinium chloride → HCID 68878912, compound

HRID 1363365Notes

Reaction equation

HRID 1363365 reaction equation
[OH:1][CH2:2][C@H:3]1[C@H:7]([C:8]2[C:9]([O:29]C)=[CH:10][C:11]([O:27]C)=[C:12]3[C:17]=2[O:16][C:15]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=2[O:24]C)=[CH:14][C:13]3=[O:26])[CH2:6][CH2:5][N:4]1[CH3:31].Cl.N1C=CC=CC=1>>[OH:27][C:11]1[CH:10]=[C:9]([OH:29])[C:8]([C@@H:7]2[CH2:6][CH2:5][N:4]([CH3:31])[C@H:3]2[CH2:2][OH:1])=[C:17]2[C:12]=1[C:13](=[O:26])[CH:14]=[C:15]([C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=1[OH:24])[O:16]2

Participants

3

Reactant 2

HCID 10176127Pyridinium chlorideHCID 68881133HCID 68881133, compound

Product 1

HCID 68878912HCID 68878912, compound

Procedure

Compound of example 95 (0.4 g, 0.9 mmol) was demethylated using pyridine hydrochloride (6 g, 52.0 mmol) as described in example 17 to obtain the title compound.

Sources & evidence

ORD record
ord-5cee8cde622c483ba263d1cfa6d109cb
Source dataset
uspto-grants-2011_02
Patent number
US07884127B2

Reaction notes

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