Sodium Hydroxide → HCID 131728674, compound

HRID 1363382Notes

Reaction equation

HRID 1363382 reaction equation
[C:1]([C:4]1[C:5]([OH:32])=[C:6]([C@@H:14]2[CH2:19][CH2:18][N:17]([C:20]3[CH:25]=[CH:24][C:23]([O:26][CH3:27])=[CH:22][CH:21]=3)[CH2:16][C@H:15]2[O:28]C(=O)C)[C:7]([O:12][CH3:13])=[CH:8][C:9]=1[O:10][CH3:11])(=[O:3])[CH3:2].[OH-].[Na+]>CO>[OH:32][C:5]1[C:6]([C@@H:14]2[CH2:19][CH2:18][N:17]([C:20]3[CH:21]=[CH:22][C:23]([O:26][CH3:27])=[CH:24][CH:25]=3)[CH2:16][C@H:15]2[OH:28])=[C:7]([O:12][CH3:13])[CH:8]=[C:9]([O:10][CH3:11])[C:4]=1[C:1](=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 131728675HCID 131728675, compound

Product 1

HCID 131728674HCID 131728674, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Compound of example 120 (0.25 g, 0.5 mmol) in MeOH (2 mL) was subjected to hydrolysis using 10% aqueous NaOH (2.0 mL) as given in example 6 to obtain the title compound.

Sources & evidence

ORD record
ord-4f9f538b06134cfa8d5302c11e0fec74
Source dataset
uspto-grants-2011_02
Patent number
US07884127B2

Reaction notes

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