Triethylamine → HCID 131728676, compound

Participants

Reaction Steps

Compound of example 122 (1.7 g, 3.2 mmol) was subjected to ring contraction as described in example 3, method A using methanesulfonyl chloride (0.448 g, 0.3 mL, 3.9 mmol), triethylamine (0.66 g, 0.95 mL, 6.5 mmol). The sulfonyl ester was treated with anhydrous sodium acetate (1.06 g, 13 mmol) to furnish the title compound.

Provenance & Evidence