Sodium Hydroxide → HCID 131728677, compound

HRID 1363385Notes

Reaction equation

HRID 1363385 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[O:9][C:10]2[C:15]([C:16](=[O:18])[CH:17]=1)=[C:14]([O:19][CH3:20])[CH:13]=[C:12]([O:21][CH3:22])[C:11]=2[C@@H:23]1[CH2:27][CH2:26][N:25]([C:28]2[CH:33]=[CH:32][C:31]([O:34][CH3:35])=[CH:30][CH:29]=2)[C@H:24]1[CH2:36][O:37]C(=O)C.[OH-].[Na+]>CO>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[O:9][C:10]2[C:15]([C:16](=[O:18])[CH:17]=1)=[C:14]([O:19][CH3:20])[CH:13]=[C:12]([O:21][CH3:22])[C:11]=2[C@@H:23]1[CH2:27][CH2:26][N:25]([C:28]2[CH:29]=[CH:30][C:31]([O:34][CH3:35])=[CH:32][CH:33]=2)[C@H:24]1[CH2:36][OH:37]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 131728676HCID 131728676, compound

Product 1

HCID 131728677HCID 131728677, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Compound of example 123 (1.1 g, 1.94 mmol) in MeOH (5 mL) was hydrolyzed using 5% methanolic NaOH (5 mL) at 50° C. as described in example 4 to get the title compound.

Workup

  1. customat 50° C.

Sources & evidence

ORD record
ord-1111903a83894768bcff86e4bc1a0abb
Source dataset
uspto-grants-2011_02
Patent number
US07884127B2

Reaction notes

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