Pyridinium chloride → HCID 131728686, compound

HRID 1363393Notes

Reaction equation

[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[O:9][C:10]2[C:15]([C:16](=[O:18])[CH:17]=1)=[C:14]([O:19]C)[CH:13]=[C:12]([O:21]C)[C:11]=2[C@@H:23]1[CH2:27][CH2:26][N:25]([CH2:28][CH2:29][CH3:30])[C@H:24]1[CH2:31][OH:32].Cl.N1C=CC=CC=1>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[O:9][C:10]2[C:15]([C:16](=[O:18])[CH:17]=1)=[C:14]([OH:19])[CH:13]=[C:12]([OH:21])[C:11]=2[C@@H:23]1[CH2:27][CH2:26][N:25]([CH2:28][CH2:29][CH3:30])[C@H:24]1[CH2:31][OH:32]

Participants

Reactant 2

HCID 10176127Pyridinium chloride

HCID 131728684HCID 131728684, compound

Product 1

HCID 131728686HCID 131728686, compound

Procedure

Following the procedure in example 17, compound of example 131 (0.155 g, 0.33 mmol) was demethylated using pyridine hydrochloride (2.0 g, 17.3 mmol) to obtain the title compound.

Sources & evidence

ORD record: ord-04dd051d35f240db98089e0674f3cd95
Source dataset: uspto-grants-2011_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07884127B2

Reaction notes

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