Nitric Acid → 2-Bromo-5-nitrobenzoic acid

HRID 1363402Notes

Reaction equation

HRID 1363402 reaction equation
[Br:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].OS(O)(=O)=O.[N+:16]([O-])([OH:18])=[O:17]>>[Br:1][C:2]1[CH:10]=[CH:9][C:8]([N+:16]([O-:18])=[O:17])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5]

Participants

4

Reactant 3

HCID 944Nitric AcidHCID 1118Sulfuric AcidHCID 69402-Bromobenzoic acid

Product 1

HCID 2430252-Bromo-5-nitrobenzoic acid

Procedure

2-Bromobenzoic acid (10 g, 49.75 mmol) was added in portions with stirring to an ice cold nitrating mixture of 98% H2SO4 (25 mL) and 69% HNO3 (12 mL) maintaining the temperature of the mixture below 5° C. The reaction mixture was stirred for 1 h. below 5° C. It was poured into ice water (200 mL). The white crystalline product obtained was filtered, washed with water and dried.

Workup

  1. temperaturemaintaining the temperature of the mixture below 5° C
  2. customThe white crystalline product obtained
  3. filtrationwas filtered
  4. washwashed with water
  5. customdried

Sources & evidence

ORD record
ord-e54417ab03e64115ad4bf16627288e6c
Source dataset
uspto-grants-2011_02
Patent number
US07884127B2

Reaction notes

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