HRID1363515

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID52911268

3-Amino-5-bromo-1-methylpyridin-2(1H)-one

C6H7BrN2O

结构：Cc1c(NC(=O)c2cc3c(s2)CCCC3)cccc1-c1cn(C)c(=O)c([O-])n1.[Na+]

HCID57625105

未命名化合物

PRODUCTS

生成物

结构：Cc1c(NC(=O)c2cc3c(s2)CCCC3)cccc1-c1cc(N)c(=O)n(C)c1

HCID57625113

未命名化合物

收率 28%

PROCEDURE

实验过程

Using the same general procedure as described for the preparation of 10, 42 (3.67 g) gave a 28% yield (2.10 g) of 43 as a yellow solid: mp 210-211° C.; 1H NMR (500 MHz, DMSO-d6) δ 9.78 (bs, 1H), 7.65 (s, 1H), 7.25 (dd, 1H, J=1.5, 8.0 Hz), 7.21 (t, 1H, J=7.5 Hz), 7.09 (dd, 1H, J=1.0, 7.0 Hz), 6.89 (d, 1H, J=2.0 Hz), 6.43 (d, 1H, J=2.5 Hz), 5.19 (bs, 2H), 3.49 (s, 3H), 2.75 (m, 2H), 2.62 (m, 2H), 2.12 (s, 3H), 1.77 (m, 4H); MS (ESI+) m/z 394 (M+H).