HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 57515536, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 57515537 | HCID 57515537 | — |
| Product | HCID 57515536 | HCID 57515536 | 77.1% |
Reaction Steps
A mixture of 4-[(4-amino-2-methyl-1H-imidazo[4,5-c][1,5]naphthyridin-1-yl)methyl]piperidin-4-ol dihydrochloride (0.80 g) and 1N sodium hydroxide (8 mL) was sonicated for 2 minutes. A solid was isolated by filtration, washed with water, and dried under high vacuum at 100° C. to provide 0.50 g of 4-[(4-amino-2-methyl-1H-imidazo[4,5-c][1,5]naphthyridin-1-yl)methyl]piperidin-4-ol as a yellow powder, mp>260.0° C. Anal. Calcd for C16H20N6O C, 61.52; H, 6.45; N, 26.90. Found: C, 61.23; H, 6.39; N, 26.92.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07884207B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-78421503bac5488cb5e8e787d9b04469 |
| Source note | uspto-grants-2011_02 |