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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1363615Generated: October 29, 2026

Sodium Hydroxide → HCID 57515536, compound

https://huagongshe.com/reaction/1363615

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 57515537HCID 57515537—
ProductHCID 57515536HCID 5751553677.1%

Reaction Steps

A mixture of 4-[(4-amino-2-methyl-1H-imidazo[4,5-c][1,5]naphthyridin-1-yl)methyl]piperidin-4-ol dihydrochloride (0.80 g) and 1N sodium hydroxide (8 mL) was sonicated for 2 minutes. A solid was isolated by filtration, washed with water, and dried under high vacuum at 100° C. to provide 0.50 g of 4-[(4-amino-2-methyl-1H-imidazo[4,5-c][1,5]naphthyridin-1-yl)methyl]piperidin-4-ol as a yellow powder, mp>260.0° C. Anal. Calcd for C16H20N6O C, 61.52; H, 6.45; N, 26.90. Found: C, 61.23; H, 6.39; N, 26.92.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07884207B2
Source datasetuspto-grants-2011_02
ORD IDord-78421503bac5488cb5e8e787d9b04469
Source noteuspto-grants-2011_02