Dimethylformamide → Benzaldehyde, 4-(diphenylamino)-

Participants

Reaction Steps

To a 300 ml four-neck flask were added 17.0 g (77 mmol) of 1,1-diphenylhydrazine hydrochloride obtained in Comparative Example 2, 21.1 g (77 mmol) of p-diphenylaminobenzaldehyde, and 70 g of DMF, followed by stirring at 40 to 45° C. for 3 hours. The reaction was traced by thin-layer chromatography. After, the completion of the reaction, 100 g of methanol was added and precipitated crystals were filtered off to obtain 32.3 g of p-diphenylaminobenzaldehyde=diphenylhydrazone. The yield was 95.4% based on the starting 1,1-diphenylhydrazine, the over all yield from the starting diphenylamine was 77.0%, and the purity determined by high-performance liquid chromatography was 98.2%.

Provenance & Evidence