HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 16101137, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethyl Propionate | HCID 7749 | — |
| Reactant | Cyclohexanone | HCID 7967 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | [2-(3-Cyclohexyl-3-phenethylureido)-thiazol-5-ylsulfanyl]-acetic acid | HCID 11993791 | — |
| Reactant | HCID 12510228 | HCID 12510228 | — |
| Product | HCID 16101137 | HCID 16101137 | — |
Reaction Steps
Prepared as described for the synthesis of [2-(3-cyclohexyl-3-phenethyl-ureido)-thiazol-5-ylsulfanyl]-acetic acid, from 2-(1-cyclohexenyl)ethylamine hydrochloride, cyclohexanone and 2-amino-thiazol-5-ylsulfanyl)-propionic acid ethyl ester. The hydrochloride was added one equivalent DIPEA prior to the reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07884210B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-4f0524820f6d44039ce0e89cc8a6e4db |
| Source note | uspto-grants-2011_02 |