HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 178446661, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethyl Propionate | HCID 7749 | — |
| Reactant | 3-Methyl-2-butenal | HCID 61020 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | [2-(3-Cyclohexyl-3-phenethylureido)-thiazol-5-ylsulfanyl]-acetic acid | HCID 11993791 | — |
| Product | HCID 178446661 | HCID 178446661 | — |
Reaction Steps
Prepared as described for the synthesis of [2-(3-cyclohexyl-3-phenethyl-ureido)-thiazol-5-ylsulfanyl]-acetic acid, from 4-trans-methyl-cyclohexylamine hydrochloride, 3-methyl-but-2-enal and 2-amino-thiazol-5-ylsulfanyl)-propionic acid ethyl ester. The hydrochloride was added one equivalent DIPEA prior to the reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07884210B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-6912e7c29bfa42d08576bd6d07d21269 |
| Source note | uspto-grants-2011_02 |