Butylamine → HCID 57668340, compound

HRID 1363728Notes

Reaction equation

HRID 1363728 reaction equation
[CH:1]1([N:7]([CH2:21][CH2:22][C:23]2[CH:28]=CC=C[CH:24]=2)[C:8](=[O:20])[NH:9][C:10]2[S:11][C:12]([S:15][CH2:16][C:17]([OH:19])=[O:18])=[CH:13][N:14]=2)CC[CH2:4][CH2:3][CH2:2]1.C(=O)CC(C)C.C(N)CCC.C(OC(=O)CSC1SC(N)=NC=1)C>>[CH2:1]([N:7]([CH2:21][CH2:22][CH:23]([CH3:24])[CH3:28])[C:8](=[O:20])[NH:9][C:10]1[S:11][C:12]([S:15][CH2:16][C:17]([OH:19])=[O:18])=[CH:13][N:14]=1)[CH2:2][CH2:3][CH3:4]

Participants

5

Reactant 4

HCID 8007ButylamineHCID 115523-MethylbutanalHCID 11993791[2-(3-Cyclohexyl-3-phenethylureido)-thiazol-5-ylsulfanyl]-acetic acidHCID 21455623Ethyl 2-(2-aminothiazol-5-ylthio)acetate

Product 1

HCID 57668340HCID 57668340, compound

Procedure

Prepared as described for the synthesis of [2-(3-cyclohexyl-3-phenethyl-ureido)-thiazol-5-ylsulfanyl]-acetic acid using isovaleraldehyde, butylamine and (2-amino-thiazol-5-ylsulfanyl)-acetic acid ethyl ester.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-54890bd5297b4a3589ca9fc81e824153
Source dataset
uspto-grants-2011_02
Patent number
US07884210B2

Reaction notes

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