Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1363776Generated: October 29, 2026

m-Aminoacetanilide → HCID 57668361, compound

https://huagongshe.com/reaction/1363776

Reaction equation

Participants

RoleNameHCIDCharge
Reactantm-AminoacetanilideHCID 7604—
ReactantCyclopropanecarboxaldehydeHCID 123114—
ReactantEthyl 2-(2-aminothiazol-5-ylthio)acetateHCID 21455623—
Reactant{2-[3-Cyclopentylmethyl-3-(3,4-difluoro-phenyl)-ureido]-thiazol-4-yl}-acetic acidHCID 57668246—
ReactantHCID 86629909HCID 86629909—
ProductHCID 57668361HCID 57668361—

Reaction Steps

The title compound was prepared via {2-[3-(3-acetylamino-phenyl)-3-cyclopropylmethyl-ureido]-thiazol-5-ylsulfanyl}-acetic acid ethyl ester in a similar manner as described for the synthesis of {2-[3-cyclopentylmethyl-3-(3,4-difluoro-phenyl)-ureido]-thiazol-4-yl}-acetic acid, using N-(3-amino-phenyl)-acetamide, cyclopropanecarboxaldehyde and (2-amino-thiazol-5-ylsulfanyl)acetic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07884210B2
Source datasetuspto-grants-2011_02
ORD IDord-cb96a34b782c4dc6b6bcb1398c37662d
Source noteuspto-grants-2011_02