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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1363799Generated: October 29, 2026

Cyclopentanecarbaldehyde → HCID 57668387, compound

https://huagongshe.com/reaction/1363799

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopentanecarbaldehydeHCID 70106—
ReactantN-(3-aminophenyl)-2-methylpropanamideHCID 960757—
ReactantEthyl 2-(2-aminothiazol-5-ylthio)acetateHCID 21455623—
Reactant{2-[3-Cyclopentylmethyl-3-(3,4-difluoro-phenyl)-ureido]-thiazol-4-yl}-acetic acidHCID 57668246—
ReactantHCID 86629931HCID 86629931—
ProductHCID 57668387HCID 57668387—

Reaction Steps

The title compound was prepared via {2-[3-cyclopentylmethyl-3-(3-isobutyrylamino-phenyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid ethyl ester in a similar manner as described for the synthesis of {2-[3-cyclopentylmethyl-3-(3,4-difluoro-phenyl)-ureido]-thiazol-4-yl}-acetic acid, using N-(3-Amino-phenyl)-isobutyramide, cyclopentanecarbaldehyde and (2-amino-thiazol-5-ylsulfanyl)acetic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07884210B2
Source datasetuspto-grants-2011_02
ORD IDord-6bfa0f88a9e3457db68d688e6c6ab9c3
Source noteuspto-grants-2011_02