HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 178427511, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | N-(9-Fluorenylmethoxycarbonyl)-O-tert-butylthreonine | HCID 6364643 | — |
| Reactant | Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 9886157 | — |
| Reactant | HCID 178427512 | HCID 178427512 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 178427511 | HCID 178427511 | — |
Reaction Steps
H-Lys(Boc)-Pro-Pro-Arg(Pmc)-t-Bu (3.55 g, 3.86 m mmol) was added to a solution of the activated acid prepared from Fmoc-Thr(t-Bu)-OH (1.6 g, 4 mmol) and HATU (1.9 g, 5 mmol) and DIEA (1.29 g, 10 mmol) in dry CH2Cl2 (25 ml) and stirred for 20 h at RT.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07884183B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-adba22e76fae4b8ba6c049f4cc7b7574 |
| Source note | uspto-grants-2011_02 |