HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl chloroformate → Benzyl 4-prop-2-ynylpiperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl chloroformate | HCID 10387 | — |
| Reactant | Tert-butyl 4-(prop-2-yn-1-yl)piperidine-1-carboxylate | HCID 18187546 | — |
| Product | Benzyl 4-prop-2-ynylpiperidine-1-carboxylate | HCID 57838958 | — |
Reaction Steps
Benzyl chloroformate (6.9 g, 40.4 mmol) was added to a solution of tert-butyl 4-(prop-2-ynyl)piperidine-1-carboxylate (1.65 g, 13.4 mmol) according to general procedure 1. Yield=0.700 g, 37%. m/z MH+=258.02. HPLC rt=10.2 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07888329B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-9b7f84505071486e92472c030079d21e |
| Source note | uspto-grants-2011_02 |