HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorophenyl chloroformate → 4-Fluorophenyl 4-(prop-2-ynyl)piperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorophenyl chloroformate | HCID 2733256 | — |
| Reactant | Tert-butyl 4-(prop-2-yn-1-yl)piperidine-1-carboxylate | HCID 18187546 | — |
| Product | 4-Fluorophenyl 4-(prop-2-ynyl)piperidine-1-carboxylate | HCID 57838902 | — |
Reaction Steps
4-(fluoro)phenyl chloroformate (5.00 g, 28.6 mmol) was added to a solution of tert-butyl 4-(prop-2-ynyl)piperidine-1-carboxylate (4.90 g, 21.9 mmol) according to general procedure 1. Yield=5.54 g, 99%. m/z MH+=262.03. HPLC rt=10.6 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07888329B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-9188c7963ce546ea9d3c49a7738b11b2 |
| Source note | uspto-grants-2011_02 |