HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Tolyl chloroformate → 4-Methylphenyl 4-(prop-2-ynyl)piperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Tolyl chloroformate | HCID 70304 | — |
| Reactant | Tert-butyl 4-(prop-2-yn-1-yl)piperidine-1-carboxylate | HCID 18187546 | — |
| Product | 4-Methylphenyl 4-(prop-2-ynyl)piperidine-1-carboxylate | HCID 57838914 | — |
Reaction Steps
4-(methyl)phenyl chloroformate (5.00 g, 29.3 mmol) was added to a solution of tert-butyl 4-(prop-2-ynyl)piperidine-1-carboxylate (5.03 g, 22.6 mmol) according to general procedure 1. Yield=5.20 g, 90%. m/z MH+=258.11. HPLC rt=13.0 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07888329B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-4e2d1c453d944ee8997bda2d9d272c1b |
| Source note | uspto-grants-2011_02 |