HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorophenyl chloroformate → 4-Chlorophenyl 4-(prop-2-ynyl)piperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorophenyl chloroformate | HCID 139059 | — |
| Reactant | Tert-butyl 4-(prop-2-yn-1-yl)piperidine-1-carboxylate | HCID 18187546 | — |
| Product | 4-Chlorophenyl 4-(prop-2-ynyl)piperidine-1-carboxylate | HCID 57838884 | — |
Reaction Steps
4-(chloro)phenyl chloroformate (5.00 g, 26.2 mmol) was added to a solution of tert-butyl 4-(prop-2-ynyl)piperidine-1-carboxylate (5.50 g, 20.1 mmol) according to general procedure 1. Yield=4.83 g, 86%. m/z MH+=278.13. HPLC rt=13.0 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07888329B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-3ded118b43b440879489cc324b238507 |
| Source note | uspto-grants-2011_02 |