HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxyphenyl chloroformate → 2-Methoxyphenyl 4-(prop-2-ynyl)piperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxyphenyl chloroformate | HCID 3362143 | — |
| Reactant | Tert-butyl 4-(prop-2-yn-1-yl)piperidine-1-carboxylate | HCID 18187546 | — |
| Product | 2-Methoxyphenyl 4-(prop-2-ynyl)piperidine-1-carboxylate | HCID 57838876 | — |
Reaction Steps
2-(methoxy)phenyl chloroformate (5.00 g, 26.8 mmol) was added to a solution of tert-butyl 4-(prop-2-ynyl)piperidine-1-carboxylate (4.60 g, 20.6 mmol) according to general procedure 1. Yield=5.03 g, 89%. m/z MH+=274.04. HPLC rt=8.7 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07888329B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-95167c31902948bda7775232eb67c910 |
| Source note | uspto-grants-2011_02 |