Bromine → 2-Bromo-5-methylcyclohexane-1,3-dione

HRID 1364087Notes

Reaction equation

HRID 1364087 reaction equation
[CH3:1][CH:2]1[CH2:7][C:6](=[O:8])[CH2:5][C:4](=[O:9])[CH2:3]1.[Br:10]Br>CC(O)=O>[Br:10][CH:5]1[C:6](=[O:8])[CH2:7][CH:2]([CH3:1])[CH2:3][C:4]1=[O:9]

Participants

4

Reactant 2

HCID 24408BromineHCID 4580955-Methylcyclohexane-1,3-dione

Product 1

HCID 669327192-Bromo-5-methylcyclohexane-1,3-dione

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

To a stirred solution of 5-methylcyclohexane-1,3-dione (1.26 g, 10 mmol) in AcOH (20 mL) at r.t. was added bromine (1.6 g, 0.51 mL, 10 mmol) dropwise. The reaction was carried out according to Method A to give the title compound in quantitative yield as a light brown solid which was used without further purification. LCMS (ES+) 204.9 (M+H)+.

Sources & evidence

ORD record
ord-a0f96e54b7204c0797f1452268b7b049
Source dataset
uspto-grants-2011_02
Patent number
US07888344B2

Reaction notes

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