Dichloromethane → HCID 66939648, compound

Participants

Reaction Steps

To benzylacrylate (100 mg, 0.617 mmol) in ethanol (2 mL) are added triethylamine (95 uL, 0.679 mmol) and 2-propanethiol (58 uL, 0.617 mmol). After stirring at rt during 2 h, the solvent is evaporated to give a residue which is treated with dichloromethane and water. The organic phase is dried and evaporated to afford a colorless oil before purification by preparative HPLC (Column Waters C18 ODB 5 μm 19×50, Gradient: 0-2.5 min 5% ACN, 2.5-12.5 min 5-100% ACN, 12.5-15 min 100% ACN) to yield the title compound.

Provenance & Evidence