Morpholine → HCID 63900315, compound

HRID 1364184Notes

Reaction equation

HRID 1364184 reaction equation
[CH3:1][O:2][C:3](=[O:9])[CH2:4][S:5](Cl)(=[O:7])=[O:6].[NH:10]1[CH2:15][CH2:14][O:13][CH2:12][CH2:11]1>ClCCl>[CH3:1][O:2][C:3](=[O:9])[CH2:4][S:5]([N:10]1[CH2:15][CH2:14][O:13][CH2:12][CH2:11]1)(=[O:7])=[O:6]

Participants

4

Reactant 2

HCID 8083MorpholineHCID 11435213Methyl (chlorosulfonyl)acetate

Product 1

HCID 63900315HCID 63900315, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To chlorosulfonyl-acetic acid methyl ester (3.39 g, 19.6 mmol) in dichloromethane (50 mL) is added morpholine (8.6 mL, 98 mmol). The resulting mixture is stirred at rt during 2 h and the solvent is evaporated to yield the title compound.

Workup

  1. customthe solvent is evaporated

Sources & evidence

ORD record
ord-fa65c5f72b85481c86a2cdd0e878c6e9
Source dataset
uspto-grants-2011_02
Patent number
US07888351B2

Reaction notes

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