HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Nitrotoluene-4-sulphonamide → 3-amino-4-methylbenzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Nitrotoluene-4-sulphonamide | HCID 81385 | — |
| Catalyst | Platinum oxide (PtO) | HCID 82844 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-amino-4-methylbenzenesulfonamide | HCID 235510 | 68% |
Reaction Steps
A solution of 4-methyl-3-nitrobenzenesulfonamide (2.1 g) and platinum oxide (210 mg) in methanol (50 ml) was stirred under hydrogen atmosphere at room temperature for 6 hours. The insoluble compound was filtered out, then the filtrate was concentrated. The residue was recrystallized from hexane/acetone to obtain the title compound (1.23 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07888348B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-e3e737d437b34accb85b42a96378c49c |
| Source note | uspto-grants-2011_02 |