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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1364310Generated: October 28, 2026

2-Nitrotoluene-4-sulphonamide → 3-amino-4-methylbenzenesulfonamide

https://huagongshe.com/reaction/1364310

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Nitrotoluene-4-sulphonamideHCID 81385—
CatalystPlatinum oxide (PtO)HCID 82844—
SolventMethanolHCID 887—
Product3-amino-4-methylbenzenesulfonamideHCID 23551068%

Reaction Steps

A solution of 4-methyl-3-nitrobenzenesulfonamide (2.1 g) and platinum oxide (210 mg) in methanol (50 ml) was stirred under hydrogen atmosphere at room temperature for 6 hours. The insoluble compound was filtered out, then the filtrate was concentrated. The residue was recrystallized from hexane/acetone to obtain the title compound (1.23 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07888348B2
Source datasetuspto-grants-2011_02
ORD IDord-e3e737d437b34accb85b42a96378c49c
Source noteuspto-grants-2011_02