Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-Methylaniline → 6-(5-Chloro-2-methoxybenzyl)-n-{(1r)-1-[(methylanilino)carbonyl]propyl}-3,7-dioxo-1,4-diazepan-1-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-Methylaniline | HCID 7515 | — |
| 반응물 | Glycine tert-butyl ester hydrochloride | HCID 2725036 | — |
| 반응물 | Tert-butyl {[2-({[6-(5-chloro-2-methoxybenzyl)-3,7-dioxo-1,4-diazepan-1-yl]carbonyl}amino)butanoyl]amino}acetate | HCID 76588771 | — |
| 생성물 | 6-(5-Chloro-2-methoxybenzyl)-n-{(1r)-1-[(methylanilino)carbonyl]propyl}-3,7-dioxo-1,4-diazepan-1-carboxamide | HCID 57670908 | — |
반응 단계
Instead of the starting material compound of Example 220, that is, glycine tert-butyl ester hydrochloride, N-methylaniline was used for the similar procedure as in Example 220 to obtain the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07888348B2 |
| 출처 데이터셋 | uspto-grants-2011_02 |
| ORD ID | ord-7f263ef0f65d4861970cd8cf6c3793fd |
| 출처 메모 | uspto-grants-2011_02 |