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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1364394Generated: October 31, 2026

Pivalaldehyde → 1-(4-Chlorophenyl)-2,2-dimethylpropanol

https://huagongshe.com/reaction/1364394

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPivalaldehydeHCID 12417—
ReactantHCID 178478191HCID 178478191—
SolventDiethyl EtherHCID 3283—
Product1-(4-Chlorophenyl)-2,2-dimethylpropanolHCID 13095420—

Reaction Steps

Grignard reaction of trimethylacetaldehyde (240.0 mg; 2.8 mmol) with 4-chlorophenylmagnesium bromide in anhydrous ether afforded 0.58 grams of 1-(4-chlorophenyl)-2,2-dimethylpropanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07888366B2
Source datasetuspto-grants-2011_02
ORD IDord-105a5ca204fb443a804a6099b738a56e
Source noteuspto-grants-2011_02