3-Methyl-2-thenoic acid → HCID 58614804, compound

HRID 1364642Notes

Reaction equation

HRID 1364642 reaction equation
[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][C:3]=1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=1.[CH3:15][C:16]1[CH:20]=[CH:19][S:18][C:17]=1[C:21](O)=[O:22]>>[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([NH:6][C:21]([C:17]2[S:18][CH:19]=[CH:20][C:16]=2[CH3:15])=[O:22])=[CH:4][C:3]=1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=1

Participants

3

Reactant 2

HCID 902693-Methyl-2-thenoic acidHCID 401519254-Chloro-3-(pyridin-2-yl)aniline

Product 1

HCID 58614804HCID 58614804, compound

Procedure

Procedure G was used to couple 4-chloro-3-(pyridin-2-yl)aniline (50 mg) and 3-methyl-2-thiophenecarboxylic acid to produce N-(4-chloro-3-(pyridin-2-yl)phenyl)-3-methylthiophene-2-carboxamide. MS (Q1) 329.0 (M)+.

Sources & evidence

ORD record
ord-bf6eb6de395d4cf6a73df1c9b2a02470
Source dataset
uspto-grants-2011_02
Patent number
US07888364B2

Reaction notes

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