3-Methanesulfonylbenzoic acid → N-(4-chloro-3-(pyridin-2-yl)phenyl)-3-(methylsulfonyl)benzamide

HRID 1364644Notes

Reaction equation

HRID 1364644 reaction equation
[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][C:3]=1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=1.[CH3:15][S:16]([C:19]1[CH:20]=[C:21]([CH:25]=[CH:26][CH:27]=1)[C:22](O)=[O:23])(=[O:18])=[O:17]>>[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([NH:6][C:22](=[O:23])[C:21]2[CH:25]=[CH:26][CH:27]=[C:19]([S:16]([CH3:15])(=[O:18])=[O:17])[CH:20]=2)=[CH:4][C:3]=1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=1

Participants

3

Reactant 2

HCID 2203803-Methanesulfonylbenzoic acidHCID 401519254-Chloro-3-(pyridin-2-yl)aniline

Product 1

HCID 45485696N-(4-chloro-3-(pyridin-2-yl)phenyl)-3-(methylsulfonyl)benzamide

Procedure

Procedure G was used to couple 4-chloro-3-(pyridin-2-yl)aniline and 3-(methanesulfonyl)benzoic acid to produce N-(4-chloro-3-(pyridin-2-yl)phenyl)-3-(methylsulfonyl)benzamide. MS (Q1) 387.2 (M)+.

Sources & evidence

ORD record
ord-f4e4b3ed8cd048618e3033d7bd68c844
Source dataset
uspto-grants-2011_02
Patent number
US07888364B2

Reaction notes

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